Dr. VR. Muthukkaruppan worked as Professor of Immunology for over three decades in Madurai Kamaraj University where teaching at Master’s level and Research at Ph.D. level were established in the field of Immunology. During this period, he has identified the origin of T and B lymphocytes in a reptile from which both mammals and birds evolved. His major interest has been the development of candidate vaccine and diagnosis for murine typhoid using purified porine for which he also developed several monoclonal antibodies. As Founder-Director of Research, Dr. Muthukkaruppan has organized the research laboratory at Aravind Medical Research Foundation and contributed to the understanding of the pathogenic mechanism of diabetic retinopathy, corneal epithelial stem cells, Immunology of uveitis. At present, as Advisor he is interested in developing